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- 品牌：Invivogen
- 產(chǎn)地：國外
- 型號：詳詢
- 貨號：bb-ifnt1
- 發(fā)布日期： 2023-03-30
- 更新日期： 2024-08-12
| 產(chǎn)地 | 國外 |
| 保存條件 | -20℃保存 |
| 品牌 | Invivogen |
| 貨號 | bb-ifnt1 |
| 用途 | 科研 |
| 組織來源 | 詳詢 |
| 細胞形態(tài) | 詳詢 |
| 是否是腫瘤細胞 | 是 |
| 保質(zhì)期 | 詳詢 |
| 器官來源 | 詳詢 |
| 免疫類型 | 詳詢 |
| 品系 | 詳詢 |
| 生長狀態(tài) | 詳詢 |
| 物種來源 | 詳詢 |
| 包裝規(guī)格 | 詳詢 |
| 是否進口 | 是 |
Cell line description:
B16-Blue™ IFN-α/β cells derive from the murine B16 melanoma cell line of C57BL/6 origin after stable transfection with a SEAP (secreted embryonic alkaline phosphatase) reporter gene under the control of the IFN-α/β-inducible ISG54 promoter enhanced by a multimeric ISRE. These cells do not respond to IFN-γ, due to the inactivation of the IFN-γ receptor.
B16-Blue™ IFN-α/β cells respond specifically to mIFN-α/β and do not respond to human IFN-α/β. Stimulation of these cells with murine IFN-α or IFN-β, or type I IFN inducers, such as poly(I:C), poly(dA:dT) or 5’ppp-dsRNA delivered intracellularly, triggers the production of SEAP by the activation of the IRF-inducible promoter. Levels of SEAP can be easily monitored using the detection medium QUANTI-Blue™ Solution.
