- 品牌:賽默飛
- 產(chǎn)地:國外
- 型號:詳詢
- 貨號:PA5-116785
- 發(fā)布日期: 2022-08-29
- 更新日期: 2024-08-12
產(chǎn)地 | 國外 |
品牌 | 賽默飛 |
貨號 | PA5-116785 |
保存條件 | -20° C, Avoid Freeze/Thaw Cycles |
用途 | 詳詢 |
應(yīng)用范圍 | ICC/IF WB IHC (P) |
抗原來源 | 詳詢 |
CAS編號 | |
保質(zhì)期 | 詳詢 |
抗體名 | Histone H3ac (pan-acetyl) Polyclonal Antibody |
是否單克隆 | 否 |
克隆性 | 是 |
靶點 | 詳詢 |
適應(yīng)物種 | Human, Mouse, Rat |
形態(tài) | Liquid |
宿主 | Rabbit |
標記物 | 詳詢 |
包裝規(guī)格 | 詳詢 |
純度 | 詳詢% |
亞型 | IgG |
標識物 | 詳詢 |
濃度 | 1.1 mg/mL% |
免疫原 | 詳詢 |
是否進口 | 是 |
產(chǎn)品信息
應(yīng)用 |
建議稀釋比 |
免疫印跡 (WB) |
1:500-1:2,000 |
免疫組化(石蠟) (IHC (P)) |
1:50-1:200 |
免疫細胞化學(xué) (ICC/IF) |
1:50-1:200 |
產(chǎn)品規(guī)格
|
|
---|---|
種屬反應(yīng) |
Human, Mouse, Rat |
宿主/亞型 |
Rabbit / IgG |
分類 |
Polyclonal |
類型 |
Antibody |
抗原 |
A synthetic peptide of human Acetyl-Histone H3-K9/K14/K18/K23/K27 |
偶聯(lián)物 |
Unconjugated |
形式 |
Liquid |
濃度 |
1.1 mg/mL |
純化類型 |
Affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
內(nèi)含物 |
0.02% sodium azide |
保存條件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2901416 |
產(chǎn)品詳細信息
Positive Samples: HeLa, NIH/3T3, C6
靶標信息
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.