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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：206830
- cas：1691249-45-2
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 206830 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 5.0mg; 10.0mg; 25.0mg; 50.0mg; |
| CAS編號 | 1691249-45-2 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
產(chǎn)品描述: 贊魯替尼 ，也被稱為BGB-3111，是一種有效且高度選擇性的小分子BTK抑制劑，可用于多種淋巴瘤的潛在 。BGB-3111選擇性地結(jié)合并抑制BTK的活性，并阻止B細(xì)胞抗原受體（BCR）信號通路的激活。扎努布替尼具有S-異構(gòu)體CAS 1691249-45-2。
產(chǎn)品名稱: Zanubrutinib
CAS#: 1691249-45-2 (S-isomer)
分子式: C27H29N5O3
Exact Mass: 471.227
分子量: 471.561
元素分析: C, 68.77; H, 6.20; N, 14.85; O, 10.18
Synonym: BGB-3111; BGB 3111; BGB3111; Zanubrutinib; Brukinsa.
IUPAC/Chemical Name: (7S)-4,5,6,7-Tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
InChi Key: RNOAOAWBMHREKO-QFIPXVFZSA-N
InChi Code: InChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)/t22-/m0/s1
SMILES Code: O=C(C1=C2NCC[C@@H](C3CCN(C(C=C)=O)CC3)N2N=C1C4=CC=C(OC5=CC=CC=C5)C=C4)N
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
