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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號(hào)：100140
- cas：184475-35-2
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號(hào) | 100140 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 2.0g; 5.0g; 10.0g; 20.0g; 50.0g; 100.0g; 200.0g; 500.0g; |
| CAS編號(hào) | 184475-35-2 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
產(chǎn)品描述：吉非替尼又名ZD1839，是一種具有抗cancer活性的苯胺基喹唑啉。吉非替尼抑制包括EGFR在內(nèi)的多種酪氨酸激酶的催化活性。具體而言，該試劑與ATP與EGFR酪氨酸激酶結(jié)構(gòu)域的結(jié)合競爭，從而抑制受體自磷酸化并導(dǎo)致信號(hào)轉(zhuǎn)導(dǎo)的抑制。吉非替尼還可能誘導(dǎo)細(xì)胞周期停滯。它由阿斯利康和Teva銷售。
產(chǎn)品名稱: Gefitinib
CAS#: 184475-35-2
分子式: C22H24ClFN4O3
分子量: 446.9
元素分析: C, 59.13; H, 5.41; Cl, 7.93; F, 4.25; N, 12.54; O, 10.74
Synonym: ZD 1839; ZD1839; ZD-1839; Gefitinib; US brand name: Iressa.
IUPAC/Chemical Name: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
InChi Key: XGALLCVXEZPNRQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
SMILES Code: COC1=CC2=NC=NC(NC3=CC=C(F)C(Cl)=C3)=C2C=C1OCCCN4CCOCC4
Appearance: white solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
