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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：464562
- cas：22202-68-2
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 464562 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; |
| CAS編號 | 22202-68-2 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: α-Ketoglutaric acid is an α-keto acid and a rate-determining metabolic intermediate in the citric acid cycle in its conjugate base form, α-ketoglutarate. It is formed via oxidative decarboxylation of isocitrate by isocitrate dehydrogenase (IDH), oxidative deamination of glutamate by glutamate dehydrogenase, or by pyridoxal phosphate-dependent transamination. α-Ketoglutaric acid is decarboxylated to succinyl-CoA by α-ketoglutarate dehydrogenase, a rate limiting step in the citric acid cycle. It is a precursor of glutamine and glutamate, energy sources for enterocytes and various immune cells, and an antioxidant with roles in immune homeostasis, aging, protein synthesis, and bone development.
Name: α-KGA
CAS#: 22202-68-2
Chemical Formula: C5H6NaO5
Exact Mass:
Molecular Weight: 169.0878
Elemental Analysis: C, 35.52; H, 3.58; Na, 13.60; O, 47.31
Synonym: α-KGA; αKGA; α KGA; 2-Oxoglutaric Acid; 2 Oxoglutaric Acid; α-Ketoglutaric Acid; α Ketoglutaric Acid; α-Ketoglutaric Acid sodium salt; α Ketoglutaric Acid sodium salt;
IUPAC/Chemical Name: 2-oxopentanedioic acid, sodium salt
InChi Key: GPRYXSKURSLOCH-UHFFFAOYSA-N
InChi Code: InChI=1S/C5H6O5.Na/c6-3(5(9)10)1-2-4(7)8;/h1-2H2,(H,7,8)(H,9,10);
SMILES Code: O=C(O)C(CCC(O)=O)=O.[Na]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
