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T2AA
  • 品牌:MedKoo
  • 產(chǎn)地:美國
  • 貨號(hào):574919
  • cas:1380782-27-3
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請(qǐng)
產(chǎn)地 美國
品牌 MedKoo
貨號(hào) 574919
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 10.0mg; 50.0mg;
CAS編號(hào) 1380782-27-3
純度 >98%%
是否進(jìn)口

Description: T2AA is a proliferating cell nuclear antigen (PCNA) inhibitor that inhibits PCNA/PIP-box peptide interaction and causes DNA replication stress by stalling DNA replication forks. It inhibits PCNA interaction with DNA polymerase δ and arrests cell growth in S-phase. It also suppresses cancer cell growth.

Name: T2AA
CAS#: 1380782-27-3
Chemical Formula: C15H15I2NO3
Exact Mass: 510.9141
Molecular Weight: 511.09
Elemental Analysis: C, 35.25; H, 2.96; I, 49.66; N, 2.74; O, 9.39

Synonym: T2AA

IUPAC/Chemical Name: (S)-4-(4-(2-amino-3-hydroxypropyl)-2,6-diiodophenoxy)phenol

InChi Key: NKOSKXJRVWVXRI-JTQLQIEISA-N

InChi Code: InChI=1S/C15H15I2NO3/c16-13-6-9(5-10(18)8-19)7-14(17)15(13)21-12-3-1-11(20)2-4-12/h1-4,6-7,10,19-20H,5,8,18H2/t10-/m0/s1

SMILES Code: IC1=C(OC2=CC=C(O)C=C2)C(I)=CC(C[C@H](N)CO)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001