|
- 品牌：MedKoo
- 產(chǎn)地：美國(guó)
- 貨號(hào)：200300
- cas：606143-52-6
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國(guó) |
| 品牌 | MedKoo |
| 貨號(hào) | 200300 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g; 10.0g; 20.0g; |
| CAS編號(hào) | 606143-52-6 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells.
Synonym: AZD6244; AZD-6244; AZD 6244; ARRY142886; ARRY 142886; ARRY-142886; ARRY886; ARRY-886; ARRY 886 ; selumetinib.
IUPAC/Chemical Name: 6-[(4-bromo-2-chlorophenyl)amino]-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
InChi Key: CYOHGALHFOKKQC-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
SMILES Code: O=C(C1=C(NC2=CC=C(Br)C=C2Cl)C(F)=C3C(N(C)C=N3)=C1)NOCCO
Appearance: white solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
