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Ibrutinib 依魯替尼 936563-96-1
  • 品牌:MedKoo
  • 產(chǎn)地:美國
  • 貨號:202171
  • cas:936563-96-1
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 202171
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 100mg;200mg;500mg;1g;2g;5g
CAS編號 936563-96-1
純度 >98%%
是否進(jìn)口

產(chǎn)品描述:依魯替尼,也稱為PCI-32765,是一種有效的口服BTK抑制劑。伊布替尼結(jié)合并抑制BTK活性,防止B細(xì)胞激活和B細(xì)胞介導(dǎo)的信號傳導(dǎo),并抑制過度表達(dá)BTK的惡性B細(xì)胞的生長。2013年11月13日,美國FDA批準(zhǔn)伊布替尼用于 套細(xì)胞淋巴瘤。

產(chǎn)品名稱: Ibrutinib
CAS#: 936563-96-1
分子式: C25H24N6O2
Exact Mass: 440.19607
分子量: 440.49706
元素分析: C, 68.17; H, 5.49; N, 19.08; O, 7.26


IUPAC/Chemical Name: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one.

InChi Key: XYFPWWZEPKGCCK-GOSISDBHSA-N

InChi Code: InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)/t18-/m1/s1

SMILES Code: C=CC(N1C[C@H](N2N=C(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C52)CCC1)=O

Appearance: white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO at 80 mg / mL

Shelf Life: >5 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001